Conditional knockout of N-WASP enhanced the formation of keratinizing squamous cell carcinoma induced by KRasG12D

Conditional knockout of N-WASP enhanced the formation of keratinizing squamous cell carcinoma induced by KRasG12D

Squamous cell carcinoma (SCC) is one of the most common forms of skin cancer in humans, and Neural Wiskott-Aldrich Syndrome Protein (N-WASP) plays a crucial role in epidermal homeostasis. To elucidate the role of N-WASP in skin cancer, we generated mice which expressed constitutively active KRas (KR...

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Bibliographic Details
Main Authors: Kalailingam, Pazhanichamy, Verma, Apoorva, Lee, Ying Hui, Thanabalu, Thirumaran
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2024
Subjects:
Science::Biological sciences
Keratin Pearl
Skin Cancer
Online Access:https://hdl.handle.net/10356/173146
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Institution: Nanyang Technological University
Language: English

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https://hdl.handle.net/10356/173146

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