Structural analysis of amyloid fibrils modulated by ATP-independent disaggregase and environmental factors

Amyloid fibrils are implicated in various neurodegenerative disorders, including Alzheimer’s disease (AD) and Transforming Growth Factor Beta Induced (TGFBI)- related corneal dystrophy (CD). TGFBI-related CD is a progressive disorder where insoluble protein deposits accumulate in the corneal tissues...

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Bibliographic Details
Main Author: Low, Kimberly Jia Yi
Other Authors: Konstantin Pervushin
Format: Thesis-Doctor of Philosophy
Language:English
Published: Nanyang Technological University 2024
Subjects:
Online Access:https://hdl.handle.net/10356/173158
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Institution: Nanyang Technological University
Language: English