Mn-single-atom nano-multizyme enabled NIR-II photoacoustically monitored, photothermally enhanced ROS storm for combined cancer therapy

• Main Authors: Wang, Xiaozhe, Ren, Xiaofeng, Yang, Jie, Zhao, Zican, Zhang, Xiaoyu, Yang, Fan, Zhang, Zheye, Chen, Peng, Li, Liping, Zhang, Ruiping
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2024
• Subjects: Science::Medicine; Photothermal Therapy; Single-Atom Nanozymes
• Online Access: https://hdl.handle.net/10356/173162
• Institution: Nanyang Technological University

Rationale: To realize imaging-guided multi-modality cancer therapy with minimal side effects remains highly challenging. Methods: We devised a bioinspired hollow nitrogen-doped carbon sphere anchored with individually dispersed Mn atoms (Mn/N-HCN) via oxidation polymerization with triton micelle as...