Rifaximin potentiates clarithromycin against Mycobacterium abscessus in vitro and in zebrafish

Rifaximin potentiates clarithromycin against Mycobacterium abscessus in vitro and in zebrafish

Mycobacterium abscessus is a non-tuberculous mycobacterium (NTM) that causes chronic pulmonary infections. Because of its extensive innate resistance to numerous antibiotics, treatment options are limited, often resulting in poor clinical outcomes. Current treatment regimens usually involve a combin...

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Main Authors: Goh, Boon Chong, Larsson, Simon, Dam, Linh Chi, Ling, Sharon Yan Han, Chua, Patrina Wei Lin, Abirami, R., Singh, Samsher, Ong, Ernest Jun Long, Teo, Jeanette W. P., Ho, Peiying, Ingham, Philip William, Pethe, Kevin, Dedon, Peter C.
其他作者: Lee Kong Chian School of Medicine (LKCMedicine)
格式: Article
語言:English
出版: 2024
主題:
Medicine, Health and Life Sciences
Antibiotics
Clarithromycin
在線閱讀:https://hdl.handle.net/10356/173643
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總結:Mycobacterium abscessus is a non-tuberculous mycobacterium (NTM) that causes chronic pulmonary infections. Because of its extensive innate resistance to numerous antibiotics, treatment options are limited, often resulting in poor clinical outcomes. Current treatment regimens usually involve a combination of antibiotics, with clarithromycin being the cornerstone of NTM treatments.

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