Dynamic altruistic cooperation within breast tumors

• Main Authors: Muhammad Sufyan Bin Masroni, Lee, Kee Wah, Lee, Victor Kwan Min, Ng, Siok Bian, Law, Chao Teng, Poon, Kok Siong, Lee, Bernett Teck Kwong, Liu, Zhehao, Tan, Yuen Peng, Chng, Wee Ling, Tucker, Steven, Ngo, Lynette Su-Mien, Yip, George Wai Cheong, Nga, Min En, Hue, Susan Swee Shan, Putti, Thomas Choudary, Bay, Boon Huat, Lin, Qingsong, Zhou, Lihan, Hartman, Mikael, Loh, Tze Ping, Lakshmanan, Manikandan, Lee, Sook Yee, Tergaonkar, Vinay, Chua, Huiwen, Lee, Adeline Voon Hui, Yeo, Eric Yew Meng, Li, Mo-Huang, Chang, Chan Fong, Kee, Zizheng, Tan, Karen Mei-Ling, Tan, Soo Yong, Koay, Evelyn Siew-Chuan, Archetti, Marco, Leong, Sai Mun
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2024
• Subjects: Medicine, Health and Life Sciences; Altruism; Breast neoplasms
• Online Access: https://hdl.handle.net/10356/173761
• Institution: Nanyang Technological University

Social behaviors such as altruism, where one self-sacrifices for collective benefits, critically influence an organism's survival and responses to the environment. Such behaviors are widely exemplified in nature but have been underexplored in cancer cells which are conventionally seen as selfish competitive players. This multidisciplinary study explores altruism and its mechanism in breast cancer cells and its contribution to chemoresistance.