Metabolism of glucose activates TORC1 through multiple mechanisms in Saccharomyces cerevisiae

• المؤلفون الرئيسيون: Alfatah, Mohammad, Cui, Liang, Goh, Corinna Jie Hui, Cheng, Trishia Yi Ning, Zhang, Yizhong, Naaz, Arshia, Wong, Jin Huei, Lewis, Jacqueline, Poh, Wei Jie, Arumugam, Prakash
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2024
• الموضوعات: Medicine, Health and Life Sciences; Glucose signaling; Glycolysis
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/173930
• المؤسسة: Nanyang Technological University

Target of Rapamycin Complex 1 (TORC1) is a conserved eukaryotic protein complex that links the presence of nutrients with cell growth. In Saccharomyces cerevisiae, TORC1 activity is positively regulated by the presence of amino acids and glucose in the medium. However, the mechanisms underlying nutr...