Encapsulation of human spinal cord progenitor cells in hyaluronan-gelatin hydrogel for spinal cord injury treatment

• Main Authors: Kwokdinata, Christy, Ramanujam, Vaibavi, Chen, Jiahui, Nunes de Oliveira, Paula, Nai, Mui Hoon, Chooi, Wai Hon, Lim, Chwee Teck, Ng, Shi Yan, David, Laurent, Chew, Sing Yian
• Other Authors: School of Chemistry, Chemical Engineering and Biotechnology
• Format: Article
• Language: English
• Published: 2024
• Subjects: Engineering; Medicine, Health and Life Sciences; Neural tissue engineering; Stem cell therapy; Neural stem cells; Injectable scaffold; Induced pluripotent stem cells
• Online Access: https://hdl.handle.net/10356/173936
• Institution: Nanyang Technological University

Transplanting human induced pluripotent stem cells (iPSCs)-derived spinal cord progenitor cells (SCPCs) is a promising approach to treat spinal cord injuries. However, stem cell therapies face challenges in cell survival, cell localization to the targeted site, and control of cell differentiation. H...