Impedance-based microfluidic cytometry for label-free monitoring and on-demand microcarrier sorting

• Main Author: Gong, Lingyan
• Other Authors: Hou Han Wei
• Format: Thesis-Doctor of Philosophy
• Language: English
• Published: Nanyang Technological University 2024
• Subjects: Engineering; Medicine, Health and Life Sciences; Microfluidics; Impedance cytometry; Actuated sorting; Microcarriers; Cell aggregates; Hydrogel microparticles; Cell-based manufacturing
• Online Access: https://hdl.handle.net/10356/174073
• Institution: Nanyang Technological University

In cell-based manufacturing, three-dimensional (3D) cell cultures, including spheroids (cellular aggregates), microcarriers and hydrogel microparticles (~100-300 µm) are widely used for scaled-up cell expansion and cell processing in tissue engineering, cell therapies, etc. Conventional bioprocess s...