Multigenerational adversity impacts on human gut microbiome composition and socioemotional functioning in early childhood

• Main Authors: Querdasi, Francesca R., Enders, Craig, Karnani, Neerja, Broekman, Birit, Chong, Yap Seng, Gluckman, Peter D., Daniel, Lourdes Mary, Yap, Fabian, Eriksson, Johan G., Cai, Shirong, Chong, Mary Foong-Fong, Toh, Jia Ying, Godfrey, Keith, Meaney, Michael J., Callaghan, Bridget L.
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2024
• Subjects: Medicine, Health and Life Sciences; Intergenerational transmission; Early life adversity
• Online Access: https://hdl.handle.net/10356/174264
• Institution: Nanyang Technological University

Adversity exposures in the prenatal and postnatal period are associated with an increased risk for psychopathology, which can be perpetuated across generations. Nonhuman animal research highlights the gut microbiome as a putative biological mechanism underlying such generational risks. In a sample o...