Single-cell transcriptomics reveals maturation of transplanted stem cell–derived retinal pigment epithelial cells toward native state

Transplantation of stem cell–derived retinal pigment epithelial (RPE) cells is considered a viable therapeutic option for age-related macular degeneration (AMD). Several landmark Phase I/II clinical trials have demonstrated safety and tolerability of RPE transplants in AMD patients, albeit with limi...

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Main Authors: Parikh, Bhav Harshad, Blakeley, Paul, Regha, Kakkad, Liu, Zengping, Yang, Binxia, Bhargava, Mayuri, Wong, Daniel Soo Lin, Tan, Queenie Shu Woon, Wong, Claudine See Wei, Wang, Hao Fei, Al-Mubaarak, Abdurrahmaan, Chou, Chai, Cheung, Gemmy Chui Ming, Lim Kah-Leong, Barathi, Veluchamy Amutha, Hunziker, Walter, Lingam, Gopal, Hu, Tim Xiaoming, Su, Xinyi
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2024
Subjects:
Online Access:https://hdl.handle.net/10356/174340
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Institution: Nanyang Technological University
Language: English
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