Label-free single microparticles and cell aggregates sorting in continuous cell-based manufacturing

• Main Authors: Gong, Lingyan, He, Linwei, Lu, Nan, Petchakup, Chayakorn, Li, Holden King Ho, Tay, Chor Yong, Hou, Han Wei
• 其他作者: School of Mechanical and Aerospace Engineering
• 格式: Article
• 語言: English
• 出版: 2024
• 主題: Engineering; Cell-based manufacturing; Hydrogel microparticles
• 在線閱讀: https://hdl.handle.net/10356/174671

There is a paradigm shift in biomanufacturing toward continuous bioprocessing but cell-based manufacturing using adherent and suspension cultures, including microcarriers, hydrogel microparticles, and 3D cell aggregates, remains challenging due to the lack of efficient in-line bioprocess monitoring...