Autolysosomal acidification impairment as a mediator for TNFR1 induced neuronal necroptosis in Alzheimer's disease

Neuronal necroptosis–an emerging form of regulated cell death associated with neuroinflammatory signaling: Alzheimer ’s disease (AD) is characterized by the presence of extracellular amyloid-β (Aβ) plaques and intracellular tau neurofibrillary tangles as well as progressive neuronal loss. Recent evi...

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Bibliographic Details
Main Authors: Asimakidou, Evridiki, Reynolds, Richard, Barron, Anna M., Lo, Chih Hung
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2024
Subjects:
Online Access:https://hdl.handle.net/10356/174764
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Institution: Nanyang Technological University
Language: English