Utilizing molecular docking and cell validation to explore the potential mechanisms of lupenone attenuating the inflammatory response via NF-κB pathway
Diabetic nephropathy (DN), a common microvascular complicating disease of diabetes. Lupenone, a pentacyclic triterpenoid, has anti-inflammatory effects and can prevent type 2 diabetes mellitus and treat renal damage, however, the effects and mechanisms of lupenone in DN remain unclear. Thereby,the M...
Saved in:
Main Authors: | Wang, Xiangpei, Liu, Mei, Li, Xiaofen, Zhang, Mei, Xu, Feng, Liu, Hongyun, Wu, Hongmei |
---|---|
Other Authors: | School of Physical and Mathematical Sciences |
Format: | Article |
Language: | English |
Published: |
2024
|
Subjects: | |
Online Access: | https://hdl.handle.net/10356/174953 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Institution: | Nanyang Technological University |
Language: | English |
Similar Items
-
CYSTEINE THERAPEUTICS DEVELOPMENT FOR THE TREATMENT OF INFLAMMATORY DISEASES
by: NG MEI YING
Published: (2022) -
Atorvastatin attenuates TLR4-mediated NF-κB activation in a MyD88-dependent pathway
by: Praveen Chansrichavala, et al.
Published: (2018) -
Gamma Radiation-Induced Disruption of Cellular Junctions in HUVECs Is Mediated through Affecting MAPK/NF- κB Inflammatory Pathways
by: Wang, H., et al.
Published: (2021) -
RANKL targeted peptides inhibit osteoclastogenesis and attenuate adjuvant induced arthritis by inhibiting NF-κB activation and down regulating inflammatory cytokines
by: Naidu, V.G.M., et al.
Published: (2014) -
Effect of Siam weed extract and its bioactive component scutellarein tetramethyl ether on anti-inflammatory activity through NF-κB pathway
by: Hataichanok Pandith, et al.
Published: (2018)