Brain macrophages in Alzheimer's disease: from ontogeny to function

In the Alzheimer’s disease (AD) brain, microglia and border-associated macrophages (BAMs) undergo dynamic identity changes and display distinct activation and functional (or dysfunctional) states, which remains to be fully elucidated. Using an APP-KI AD mouse model, we demonstrated that microglia an...

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Bibliographic Details
Main Author: Wu, Xiaoting
Other Authors: Ruedl Christiane
Format: Thesis-Doctor of Philosophy
Language:English
Published: Nanyang Technological University 2024
Subjects:
Online Access:https://hdl.handle.net/10356/176738
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Institution: Nanyang Technological University
Language: English