The impact of photopigment bleaching on the human rod photoreceptor subretinal space measured via optical coherence tomography

• Main Authors: Messner, Alina, Dos Santos, Valentin Aranha, Puchner, Stefan, Stegmann, Hannes, Schlatter, Andreas, Schmidl, Doreen, Leitgeb, Rainer, Schmetterer, Leopold, Werkmeister, René M.
• Other Authors: School of Chemistry, Chemical Engineering and Biotechnology
• Format: Article
• Language: English
• Published: 2024
• Subjects: Medicine, Health and Life Sciences; Optophysiology; Intrinsic optical signal
• Online Access: https://hdl.handle.net/10356/178392
• Institution: Nanyang Technological University

PURPOSE. The purpose of this study was to investigate rod photopigment bleaching-driven intrinsic optical signals (IOS) in the human outer retina and its measurement repeatability based on a commercial optical coherence tomography (OCT) platform. METHODS. The optical path length of the rod photorece...