PESI: paratope-epitope set interaction for SARS-CoV-2 neutralization prediction

• Main Authors: Wan, Zhang, Lin, Zhuoyi, Rashid, Shamima, Ng, Shaun Yue Hao, Yin, Rui, Senthilnath, J., Kwoh, Chee Keong
• Other Authors: College of Computing and Data Science
• Format: Conference or Workshop Item
• Language: English
• Published: 2024
• Subjects: Computer and Information Science; Medicine, Health and Life Sciences; SARS-CoV-2; Paratope-epitope interaction
• Online Access: https://hdl.handle.net/10356/178506
• Institution: Nanyang Technological University

Prediction of neutralization antibodies is important for the development of effective vaccines and antibody-based therapeutics. Traditional methods rely on features based on first principles derived from the binding interface. However, they are burdened by arduous data preprocessing from a limited q...