Strategies to improve implementation of cascade testing in hereditary cancer syndromes: a systematic review

• Main Authors: Chiang, Jianbang, Chua, Ziyang, Chan, Jia Ying, Sule, Ashita Ashish, Loke, Wan Hsein, Lum, Elaine, Ong, Marcus Eng Hock, Graves, Nicholas, Ngeow, Joanne
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2024
• Subjects: Medicine, Health and Life Sciences; Cascade testing; Hereditary tumor syndrome
• Online Access: https://hdl.handle.net/10356/178841
• Institution: Nanyang Technological University

Hereditary cancer syndromes constitute approximately 10% of all cancers. Cascade testing involves testing of at-risk relatives to determine if they carry the familial pathogenic variant. Despite growing efforts targeted at improving cascade testing uptake, current literature continues to reflect poo...