Matrix metallopeptidase 9 contributes to the beginning of plaque and is a potential biomarker for the early identification of atherosclerosis in asymptomatic patients with diabetes

• Main Authors: Liu, Bingli, Su, Liping, Loo, Sze Jie, Gao, Yu, Khin, Ester, Kong, Xiaocen, Dalan, Rinkoo, Su, Xiaofei, Lee, Kok-Onn, Ma, Jianhua, Ye, Lei
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2024
• Subjects: Medicine, Health and Life Sciences; Atherosclerosis,; Ischemic heart disease
• Online Access: https://hdl.handle.net/10356/179696
• Institution: Nanyang Technological University

To determine the roles of matrix metallopeptidase-9 (MMP9) on human coronary artery smooth muscle cells (HCASMCs) in vitro, early beginning of atherosclerosis in vivo in diabetic mice, and drug naïve patients with diabetes.