Matrix metallopeptidase 9 contributes to the beginning of plaque and is a potential biomarker for the early identification of atherosclerosis in asymptomatic patients with diabetes

To determine the roles of matrix metallopeptidase-9 (MMP9) on human coronary artery smooth muscle cells (HCASMCs) in vitro, early beginning of atherosclerosis in vivo in diabetic mice, and drug naïve patients with diabetes.

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Main Authors: Liu, Bingli, Su, Liping, Loo, Sze Jie, Gao, Yu, Khin, Ester, Kong, Xiaocen, Dalan, Rinkoo, Su, Xiaofei, Lee, Kok-Onn, Ma, Jianhua, Ye, Lei
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2024
Subjects:
Online Access:https://hdl.handle.net/10356/179696
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-1796962024-08-25T15:38:00Z Matrix metallopeptidase 9 contributes to the beginning of plaque and is a potential biomarker for the early identification of atherosclerosis in asymptomatic patients with diabetes Liu, Bingli Su, Liping Loo, Sze Jie Gao, Yu Khin, Ester Kong, Xiaocen Dalan, Rinkoo Su, Xiaofei Lee, Kok-Onn Ma, Jianhua Ye, Lei Lee Kong Chian School of Medicine (LKCMedicine) Tan Tock Seng Hospital Medicine, Health and Life Sciences Atherosclerosis, Ischemic heart disease To determine the roles of matrix metallopeptidase-9 (MMP9) on human coronary artery smooth muscle cells (HCASMCs) in vitro, early beginning of atherosclerosis in vivo in diabetic mice, and drug naïve patients with diabetes. Published version This work was supported by National Natural Science Foundation of China project 81870563 (JM), China and Goh Research Foundation (LY), Singapore. 2024-08-19T01:24:39Z 2024-08-19T01:24:39Z 2024 Journal Article Liu, B., Su, L., Loo, S. J., Gao, Y., Khin, E., Kong, X., Dalan, R., Su, X., Lee, K., Ma, J. & Ye, L. (2024). Matrix metallopeptidase 9 contributes to the beginning of plaque and is a potential biomarker for the early identification of atherosclerosis in asymptomatic patients with diabetes. Frontiers in Endocrinology, 15, 1369369-. https://dx.doi.org/10.3389/fendo.2024.1369369 1664-2392 https://hdl.handle.net/10356/179696 10.3389/fendo.2024.1369369 38660518 2-s2.0-85191096679 15 1369369 en Frontiers in Endocrinology © 2024 Liu, Su, Loo, Gao, Khin, Kong, Dalan, Su, Lee, Ma and Ye. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. application/pdf
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic Medicine, Health and Life Sciences
Atherosclerosis,
Ischemic heart disease
spellingShingle Medicine, Health and Life Sciences
Atherosclerosis,
Ischemic heart disease
Liu, Bingli
Su, Liping
Loo, Sze Jie
Gao, Yu
Khin, Ester
Kong, Xiaocen
Dalan, Rinkoo
Su, Xiaofei
Lee, Kok-Onn
Ma, Jianhua
Ye, Lei
Matrix metallopeptidase 9 contributes to the beginning of plaque and is a potential biomarker for the early identification of atherosclerosis in asymptomatic patients with diabetes
description To determine the roles of matrix metallopeptidase-9 (MMP9) on human coronary artery smooth muscle cells (HCASMCs) in vitro, early beginning of atherosclerosis in vivo in diabetic mice, and drug naïve patients with diabetes.
author2 Lee Kong Chian School of Medicine (LKCMedicine)
author_facet Lee Kong Chian School of Medicine (LKCMedicine)
Liu, Bingli
Su, Liping
Loo, Sze Jie
Gao, Yu
Khin, Ester
Kong, Xiaocen
Dalan, Rinkoo
Su, Xiaofei
Lee, Kok-Onn
Ma, Jianhua
Ye, Lei
format Article
author Liu, Bingli
Su, Liping
Loo, Sze Jie
Gao, Yu
Khin, Ester
Kong, Xiaocen
Dalan, Rinkoo
Su, Xiaofei
Lee, Kok-Onn
Ma, Jianhua
Ye, Lei
author_sort Liu, Bingli
title Matrix metallopeptidase 9 contributes to the beginning of plaque and is a potential biomarker for the early identification of atherosclerosis in asymptomatic patients with diabetes
title_short Matrix metallopeptidase 9 contributes to the beginning of plaque and is a potential biomarker for the early identification of atherosclerosis in asymptomatic patients with diabetes
title_full Matrix metallopeptidase 9 contributes to the beginning of plaque and is a potential biomarker for the early identification of atherosclerosis in asymptomatic patients with diabetes
title_fullStr Matrix metallopeptidase 9 contributes to the beginning of plaque and is a potential biomarker for the early identification of atherosclerosis in asymptomatic patients with diabetes
title_full_unstemmed Matrix metallopeptidase 9 contributes to the beginning of plaque and is a potential biomarker for the early identification of atherosclerosis in asymptomatic patients with diabetes
title_sort matrix metallopeptidase 9 contributes to the beginning of plaque and is a potential biomarker for the early identification of atherosclerosis in asymptomatic patients with diabetes
publishDate 2024
url https://hdl.handle.net/10356/179696
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