Spatial proteomics of immune microenvironment in nonalcoholic steatohepatitis-associated hepatocellular carcinoma

Background and Aims: NASH-HCC is inherently resistant to immune checkpoint blockade, but its tumor immune microenvironment is largely unknown. Approach and Results: We applied the imaging mass cytometry to construct a spatially resolved single-cell atlas from the formalin-fixed and paraffin-embedded...

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Main Authors: Li, Meiyi, Wang, Lina, Cong, Liang, Wong, Chi Chun, Zhang, Xiang, Chen, Huarong, Zeng, Tao, Li, Bin, Jia, Xian, Huo, Jihui, Huang, Yuhua, Ren, Xiaoxue, Peng, Sui, Fu, Guo, Xu, Lixia, Sung, Joseph Jao Yiu, Kuang, Ming, Li, Xiaoxing, Yu, Jun
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2024
Subjects:
Online Access:https://hdl.handle.net/10356/180080
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Institution: Nanyang Technological University
Language: English