Unraveling chemical glycosylation: DFT insights into factors imparting stereoselectivity

• Main Authors: Guo, Aoxin, Xu, Yuan, Jia, Zhenhua, Loh, Teck-Peng, Liu, Xue-Wei
• Other Authors: School of Chemistry, Chemical Engineering and Biotechnology
• Format: Article
• Language: English
• Published: 2024
• Subjects: Engineering; DFT studies; Stereoselective glycosylation
• Online Access: https://hdl.handle.net/10356/180614
• Institution: Nanyang Technological University

Stereoselective chemical glycosylation reactions are pivotal for preparing manifold biologically and medically important compounds, while mechanisms of chemical glycosylation reactions remain obscure and largely speculative. Herein, we performed DFT calculations to delve into the multifaceted mechan...