Cellular uptake of phase-separating peptide coacervates

Cellular uptake of phase-separating peptide coacervates

Peptide coacervates self-assembling via liquid-liquid phase separation are appealing intracellular delivery vehicles of macromolecular therapeutics (proteins, DNA, mRNA) owing to their non-cytotoxicity, high encapsulation capacity, and efficient cellular uptake. However, the mechanisms by which thes...

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Main Authors: Shebanova, Anastasia, Perrin, Quentin Moana, Zhu, Kexin, Gudlur, Sushanth, Chen, Zilin, Sun, Yue, Huang, Congxi, Lim, Zhi Wei, Mondarte, Evan Angelo, Sun, Ruoxuan, Lim, Sierin, Yu, Jing, Miao, Yansong, Parikh, Atul N., Ludwig, Alexander, Miserez, Ali
Other Authors: School of Materials Science and Engineering
Format: Article
Language:English
Published: 2024
Subjects:
Medicine, Health and Life Sciences
Cell uptake
Drug delivery
Online Access:https://hdl.handle.net/10356/180615
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Institution: Nanyang Technological University
Language: English

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https://hdl.handle.net/10356/180615

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