Carbonyl group-assisted 1,3-amine addition to α,β-unsaturated aldehydes

An unusual 1,3-addition products were obtained when amines were reacted with α,β-unsaturated aldehydes compounds in the presence of iodine and an oxidant. The versatile unsaturated α-amino acetals are highly useful amino acid derivatives and can be converted to a wide variety of synthetically useful...

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Bibliographic Details
Main Authors: Zhang, Zhenguo, Ren, Mi, Lu, Ming-Zhu, Jia, Zhenhua, Loh, Teck-Peng
Other Authors: School of Chemistry, Chemical Engineering and Biotechnology
Format: Article
Language:English
Published: 2024
Subjects:
Online Access:https://hdl.handle.net/10356/180627
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Institution: Nanyang Technological University
Language: English