PARP4 interacts with hnRNPM to regulate splicing during lung cancer progression

• Main Authors: Lee, Yi Fei, Phua, Cheryl Zi Jin, Yuan, Ju, Zhang, Bin, Lee, May Yin, Kannan, Srinivasaraghavan, Chiu, Jasper Yui Hei, Koh, Casslynn Wei Qian, Yap, Choon Kong, Lim, Edwin Kok Hao, Chen, Jianbin, Lim, Yuhua, Lee, Jane Jia Hui, Skanderup, Anders Jacobsen, Wang, Zhenxun, Zhai, Weiwei, Tan, Nguan Soon, Verma, Chandra S., Tay, Yvonne, Tan, Daniel Shao Weng, Tam, Wai Leong
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2024
• Subjects: Medicine, Health and Life Sciences; Non-small-cell lung cancer; Functional genomics
• Online Access: https://hdl.handle.net/10356/181344
• Institution: Nanyang Technological University

Background: The identification of cancer driver genes from sequencing data has been crucial in deepening our understanding of tumor biology and expanding targeted therapy options. However, apart from the most commonly altered genes, the mechanisms underlying the contribution of other mutations to ca...