Exploring gunshot residue detection in fingerprints by functionalized particle-coupled matrix-assisted laser desorption/ionization mass spectrometry

In firearm forensic investigations, detecting gunshot residue (GSR) is crucial for linking firearms to suspects and determining firing distance for forensic reconstruction. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-ToF-MS) is emerging as a versatile and prom...

Full description

Saved in:
Bibliographic Details
Main Authors: Adav, Sunil S., Tan, Crystal Yan Wen, Low, Choon Teck, Loo, Song Wei, Ridhwan Yusoff, Gautam, Archana, Yong, Yuk Lin, Yang, Chiew Yung, Lim, Chin Chin, Ng, Kee Woei
Other Authors: School of Materials Science and Engineering
Format: Article
Language:English
Published: 2024
Subjects:
Online Access:https://hdl.handle.net/10356/181491
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Nanyang Technological University
Language: English
id sg-ntu-dr.10356-181491
record_format dspace
spelling sg-ntu-dr.10356-1814912024-12-06T15:51:03Z Exploring gunshot residue detection in fingerprints by functionalized particle-coupled matrix-assisted laser desorption/ionization mass spectrometry Adav, Sunil S. Tan, Crystal Yan Wen Low, Choon Teck Loo, Song Wei Ridhwan Yusoff Gautam, Archana Yong, Yuk Lin Yang, Chiew Yung Lim, Chin Chin Ng, Kee Woei School of Materials Science and Engineering Nanyang Environment and Water Research Institute Chemistry Gunshot residue Fingerprints In firearm forensic investigations, detecting gunshot residue (GSR) is crucial for linking firearms to suspects and determining firing distance for forensic reconstruction. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-ToF-MS) is emerging as a versatile and promising technological platform for fingerprint analysis. The capability of functionalized particles as an advanced dusting powder for visualizing latent fingerprints is widely recognized. This study aims to investigate the feasibility of employing functionalized magnetic fingerprint dusting powders for distinguishing regular and GSR fingerprints using MALDI-ToF-MS, thereby enhancing forensic evidentiary support. In this study, silica and carbon coated magnetic iron oxide particles were surface functionalized with phenyltriethoxy orthosilicate (PTEOS) or 3aminopropyl triethoxysilane (APTES) to create hydrophobic and hydrophilic particles, respectively. Donor shooters' fingerprints, both GSR-containing and regular, were analyzed using these functionalized particles coupled with MALDI-ToFMS. The results demonstrated effective fingerprint visualization and conclusive discrimination between GSR-containing and regular fingerprints through orthogonal partial least squares discriminant analysis. This technique provides enhanced sensitivity, speed, and adaptability compared to conventional methods, making it a promising choice for initial detection of GSR in latent fingerprints. Moreover, when subjected to thorough analysis using advanced instruments, it has the potential to significantly strengthen the probative value of fingerprint evidence in forensic investigations. Ministry of Home Affairs Submitted/Accepted version This work was supported by the Home Team Science and Technology Agency, Ministry of Home Affairs, Singapore (HOMHQCO20162). 2024-12-05T01:25:46Z 2024-12-05T01:25:46Z 2024 Journal Article Adav, S. S., Tan, C. Y. W., Low, C. T., Loo, S. W., Ridhwan Yusoff, Gautam, A., Yong, Y. L., Yang, C. Y., Lim, C. C. & Ng, K. W. (2024). Exploring gunshot residue detection in fingerprints by functionalized particle-coupled matrix-assisted laser desorption/ionization mass spectrometry. Analyst, 149(23), 5704-5713. https://dx.doi.org/10.1039/D4AN01260G 0003-2654 https://hdl.handle.net/10356/181491 10.1039/D4AN01260G 23 149 5704 5713 en HOMHQCO20162 Analyst © 2024 The Author(s). Published by The Royal Society of Chemistry. All rights reserved. This article may be downloaded for personal use only. Any other use requires prior permission of the copyright holder. The Version of Record is available online at http://doi.org/10.1039/D4AN01260G . application/pdf
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic Chemistry
Gunshot residue
Fingerprints
spellingShingle Chemistry
Gunshot residue
Fingerprints
Adav, Sunil S.
Tan, Crystal Yan Wen
Low, Choon Teck
Loo, Song Wei
Ridhwan Yusoff
Gautam, Archana
Yong, Yuk Lin
Yang, Chiew Yung
Lim, Chin Chin
Ng, Kee Woei
Exploring gunshot residue detection in fingerprints by functionalized particle-coupled matrix-assisted laser desorption/ionization mass spectrometry
description In firearm forensic investigations, detecting gunshot residue (GSR) is crucial for linking firearms to suspects and determining firing distance for forensic reconstruction. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-ToF-MS) is emerging as a versatile and promising technological platform for fingerprint analysis. The capability of functionalized particles as an advanced dusting powder for visualizing latent fingerprints is widely recognized. This study aims to investigate the feasibility of employing functionalized magnetic fingerprint dusting powders for distinguishing regular and GSR fingerprints using MALDI-ToF-MS, thereby enhancing forensic evidentiary support. In this study, silica and carbon coated magnetic iron oxide particles were surface functionalized with phenyltriethoxy orthosilicate (PTEOS) or 3aminopropyl triethoxysilane (APTES) to create hydrophobic and hydrophilic particles, respectively. Donor shooters' fingerprints, both GSR-containing and regular, were analyzed using these functionalized particles coupled with MALDI-ToFMS. The results demonstrated effective fingerprint visualization and conclusive discrimination between GSR-containing and regular fingerprints through orthogonal partial least squares discriminant analysis. This technique provides enhanced sensitivity, speed, and adaptability compared to conventional methods, making it a promising choice for initial detection of GSR in latent fingerprints. Moreover, when subjected to thorough analysis using advanced instruments, it has the potential to significantly strengthen the probative value of fingerprint evidence in forensic investigations.
author2 School of Materials Science and Engineering
author_facet School of Materials Science and Engineering
Adav, Sunil S.
Tan, Crystal Yan Wen
Low, Choon Teck
Loo, Song Wei
Ridhwan Yusoff
Gautam, Archana
Yong, Yuk Lin
Yang, Chiew Yung
Lim, Chin Chin
Ng, Kee Woei
format Article
author Adav, Sunil S.
Tan, Crystal Yan Wen
Low, Choon Teck
Loo, Song Wei
Ridhwan Yusoff
Gautam, Archana
Yong, Yuk Lin
Yang, Chiew Yung
Lim, Chin Chin
Ng, Kee Woei
author_sort Adav, Sunil S.
title Exploring gunshot residue detection in fingerprints by functionalized particle-coupled matrix-assisted laser desorption/ionization mass spectrometry
title_short Exploring gunshot residue detection in fingerprints by functionalized particle-coupled matrix-assisted laser desorption/ionization mass spectrometry
title_full Exploring gunshot residue detection in fingerprints by functionalized particle-coupled matrix-assisted laser desorption/ionization mass spectrometry
title_fullStr Exploring gunshot residue detection in fingerprints by functionalized particle-coupled matrix-assisted laser desorption/ionization mass spectrometry
title_full_unstemmed Exploring gunshot residue detection in fingerprints by functionalized particle-coupled matrix-assisted laser desorption/ionization mass spectrometry
title_sort exploring gunshot residue detection in fingerprints by functionalized particle-coupled matrix-assisted laser desorption/ionization mass spectrometry
publishDate 2024
url https://hdl.handle.net/10356/181491
_version_ 1819113064841084928