Priming of cancer-immunity cycle by alleviating hypoxia-induced ferroptosis resistance and immunosuppression

• المؤلفون الرئيسيون: Chen, Yun, Zuo, Mengxuan, Jana, Deblin, Zhong, Wenbin, Tan, Brynne Shu Ni, Zhang, Xiaodong, Chen, Xiaokai, Zhao, Yanli
• مؤلفون آخرون: School of Chemistry, Chemical Engineering and Biotechnology
• التنسيق: مقال
• اللغة: English
• منشور في: 2024
• الموضوعات: Engineering; Cancer-immunity cycle; Tumor microenvironment
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/181691
• المؤسسة: Nanyang Technological University

Stimulating a robust cancer-immunity cycle (CIC) holds promising potential for eliciting potent and enduring immune responses for cancer immunotherapy. However, designing a therapeutic nanomaterial capable of both enhancing tumor immunogenicity and mitigating immunosuppression is challenging and oft...