Association of plasma ceramide with decline in kidney function in patients with type 2 diabetes

• Main Authors: Gurung, Resham L., Yiamunaa, M., Tham, Wai Kin, Liu, Sylvia, Zheng, Huili, Lee, Janus, Ang, Keven, Wenk, Markus, Subramaniam, Tavintharan, Sum, Chee Fang, Torta, Federico, Liu, Jian-Jun, Lim, Su Chi
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2024
• Subjects: Medicine, Health and Life Sciences; Diabetes kidney disease; Ceramide ratio
• Online Access: https://hdl.handle.net/10356/181762
• Institution: Nanyang Technological University

Circulating ceramide levels are dysregulated in kidney disease. However, their associations with rapid decline in kidney function (RDKF) and end-stage kidney disease (ESKD) in patients with type 2 diabetes (T2D) are unknown. In this prospective study of 1746 T2D participants, we examined the associa...