Trifluoroacetic acid as a molecular probe for the dense phase in liquid-liquid phase-separating peptide systems

• المؤلفون الرئيسيون: Lim, Jessica, Chin, Sze Yuet, Miserez, Ali, Xue, Kai, Pervushin, Konstantin
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2025
• الموضوعات: Chemistry; Dense Phase; Hofmeister
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/182198

Although trifluoroacetic acid (TFA) is not typically considered a Hofmeister reagent, it has been demonstrated to modulate biocoacervation. We show that TFA can be employed to probe specific interactions in coacervating bioinspired peptide phenylalanine (Phe) 19F-labeled at a single site, altering i...