A nitroreductase-activatable metabolic reporter for covalent labeling of pathological hypoxic cells in tumorigenesis

A nitroreductase-activatable metabolic reporter for covalent labeling of pathological hypoxic cells in tumorigenesis

Aberrant hypoxic stress will initiate a cascade of pathological consequence observed prominently in tumorigenesis. Understanding of hypoxia's role in tumorigenesis is highly essential for developing effective therapeutics, which necessitates reliable tools to specifically distinguish hypoxic tu...

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Bibliographic Details
Main Authors: Wang, Zhimin, Lau, Jun Wei, Liu, Songhan, Ren, Ziheng, Gong, Zhiyuan, Liu, Xiaogang, Xing, Bengang
Other Authors: School of Chemistry, Chemical Engineering and Biotechnology
Format: Article
Language:English
Published: 2025
Subjects:
Medicine, Health and Life Sciences
Metabolic glycan engineering
Nitroreductase-activatable
Online Access:https://hdl.handle.net/10356/182206
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/182206

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