Characterization of protein-protein interactions underlying liquid-liquid phase separation in Rubisco biomolecular condensates

• Main Author: Poh, Cheng Wei
• Other Authors: Oliver Mueller-Cajar
• Format: Thesis-Doctor of Philosophy
• Language: English
• Published: Nanyang Technological University 2025
• Subjects: Medicine, Health and Life Sciences; Liquid-liquid phase separation; CO2 concentrating mechanisms; Pyrenoid; Phaeodactylum tricornutum; Rubiscondensation
• Online Access: https://hdl.handle.net/10356/182250
• Institution: Nanyang Technological University

As the gateway enzyme responsible for the assimilation of virtually all inorganic carbon into the biosphere, Rubisco is infamous for its slow and promiscuous activity. To compensate for its shortcomings, many marine phytoplanktons have evolved biophysical CO2 concentrating mechanisms (CCM) to increa...