Allylation of lactol in water

• المؤلفون الرئيسيون: Zheng, Mengxue, Gao, Wenxiu, Zhang, Lei, Yan, Kaiyu, Zhang, Zhenguo, Xie, Peizhong, Loh, Teck-Peng
• مؤلفون آخرون: School of Physical and Mathematical Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2025
• الموضوعات: Chemistry; Allylation; Water
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/182583
• المؤسسة: Nanyang Technological University

We developed a water-promoted cross-coupling of 3-hydroxyisobenzofuran-1(3H)-ones and allylic boronates under biocompatible conditions. This approach facilitates the synthesis of diverse 3-allylic phthalides with high yields and exceptional selectivity in a metal-free manner. The versatility and pra...