Biomolecular modelling of the intrinsically disordered proteins in liquid-liquid phase separation

• المؤلف الرئيسي: Hu, Zixin
• مؤلفون آخرون: Lu Lanyuan
• التنسيق: Thesis-Doctor of Philosophy
• اللغة: English
• منشور في: Nanyang Technological University 2025
• الموضوعات: Chemistry; Computer and Information Science; Medicine, Health and Life Sciences; Other; Biomolecular modelling; Coarse-grained model; Intrinsically disordered proteins/regions; Liquid-liquid phase separation; Molecular dynamics simulation
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/182665

Liquid-liquid phase separation (LLPS) is of significant biological importance and is widely reported in many biological systems. Intrinsically disordered proteins or regions (IDP/Rs) are a class of proteins or regions that lack well-folded structures and are thought to be a major driving force...