Polyphenol-based self-assembled nanomedicine for a three-pronged approach to reversing tumor immunosuppression

• Main Authors: Li, Zimu, Chen, Zirui, Shi, Kexin, Huang, Ping, Zeng, Wenfeng, Huang, Qili, Peng, Jingwen, Yang, Li, Chen, Hongzhong, Zhao, Yanli, Zeng, Xiaowei
• 其他作者: School of Chemistry, Chemical Engineering and Biotechnology
• 格式: Article
• 語言: English
• 出版: 2025
• 主題: Medicine, Health and Life Sciences; Drug delivery; Immune checkpoint blockade therapy
• 在線閱讀: https://hdl.handle.net/10356/183036
• 機構: Nanyang Technological University

The challenges of multi-pathway immune resistance and systemic toxicity caused by the direct injection of immune checkpoint inhibitors are critical factors that compromise the effectiveness of clinical immune checkpoint blockade therapy. In this context, natural polyphenols have been employed as the...