Caspase-mediated degradation of condensin I CAP-H during mitotic catastrophe.

• Main Author: Lee, Kelvin Kai Wei.
• Other Authors: Li, Hoi Yeung
• Format: Final Year Project
• Language: English
• Published: 2009
• Subjects: DRNTU::Science::Biological sciences::Cytology
• Online Access: http://hdl.handle.net/10356/18917
• Institution: Nanyang Technological University

Mitotic catastrophe is a type of cell death that occurs after failed mitosis. However, little is known about the mechanism underlying this form of cell death. Previous studies have demonstrated that the protein level of CAP-H is reduced during taxol-induced mitotic catastrophe. Depletion of CAP-H re...