Molecular mechanism of anion permeation through CFTR channel pore

Cystic fibrosis is an inherited disease caused by mutations in a single gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR), a member of ATP-binding cassette (ABC) proteins superfamily. Several approaches have been applied to determine the pore-lining domains or residues inc...

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Bibliographic Details
Main Author: Qian, Feng
Other Authors: Gong Xiandi, Alex
Format: Theses and Dissertations
Language:English
Published: 2009
Subjects:
Online Access:https://hdl.handle.net/10356/19012
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Institution: Nanyang Technological University
Language: English