Characterization of CFTR chloride channel

• Main Author: Yang, Jie
• Other Authors: Alex Law Sai Kit
• Format: Theses and Dissertations
• Language: English
• Published: 2009
• Subjects: DRNTU::Science::Biological sciences::Biochemistry
• Online Access: https://hdl.handle.net/10356/19294
• Institution: Nanyang Technological University

Cystic fibrosis (CF) is an inherited disease caused by mutations in a single gene which encodes the cystic fibrosis transmembrane conductance regulator (CFTR), a member of ATP-binding cassette (ABC) proteins superfamily. Since the genetic basis of CF was resolved in 1989 when the CFTR gene was clone...