Single-molecule study of DNA structure and dynamics by Forster Resonance Energy Transfer (FRET)

• Main Author: Ricksen Surya Winardhi.
• Other Authors: Phan Anh Tuan
• Format: Final Year Project
• Language: English
• Published: 2009
• Subjects: DRNTU::Science::Physics
• Online Access: http://hdl.handle.net/10356/19304
• Institution: Nanyang Technological University

G-quadruplex DNA is formed by tetrads of guanines. It has an immense biological importance, yet it has extreme conformational diversity. Ensemble methods is not capable of observing these structural dynamics. Single-molecule techniques has come to rescue due to its capability to probe individual...