Antibiotic delivery across the blood-brain barrier by nanoparticle system

Brain infection, especially bacterial and fungal meningitis, remains to be life-threatening disease despite the existence of numerous clinically available antibiotics. Important challenges include the antimicrobial agent transportation restricted by the blood-brain barrier (BBB) and multi-drug re...

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Main Author:	Liu, Li Hong
Other Authors:	Yang Yi Yan
Format:	Theses and Dissertations
Language:	English
Published:	2009
Subjects:	DRNTU::Engineering::Materials::Nanostructured materials
Online Access:	https://hdl.handle.net/10356/20666
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Institution:	Nanyang Technological University
Language:	English

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spelling	sg-ntu-dr.10356-206662023-03-04T16:47:39Z Antibiotic delivery across the blood-brain barrier by nanoparticle system Liu, Li Hong Yang Yi Yan Subbu S Venkatraman School of Materials Science & Engineering DRNTU::Engineering::Materials::Nanostructured materials Brain infection, especially bacterial and fungal meningitis, remains to be life-threatening disease despite the existence of numerous clinically available antibiotics. Important challenges include the antimicrobial agent transportation restricted by the blood-brain barrier (BBB) and multi-drug resistance presented by pathogenic microorganisms. The aim of this study is to design multifunctional micelles for brain delivery of antimicrobial agents. DOCTOR OF PHILOSOPHY (MSE) 2009-12-22T03:33:31Z 2009-12-22T03:33:31Z 2008 2008 Thesis Liu, L. H. (2008). Antibiotic delivery across the blood-brain barrier by nanoparticle system. Doctoral thesis, Nanyang Technological University, Singapore. https://hdl.handle.net/10356/20666 10.32657/10356/20666 en 173 p. application/pdf
institution	Nanyang Technological University
building	NTU Library
continent	Asia
country	Singapore Singapore
content_provider	NTU Library
collection	DR-NTU
language	English
topic	DRNTU::Engineering::Materials::Nanostructured materials
spellingShingle	DRNTU::Engineering::Materials::Nanostructured materials Liu, Li Hong Antibiotic delivery across the blood-brain barrier by nanoparticle system
description	Brain infection, especially bacterial and fungal meningitis, remains to be life-threatening disease despite the existence of numerous clinically available antibiotics. Important challenges include the antimicrobial agent transportation restricted by the blood-brain barrier (BBB) and multi-drug resistance presented by pathogenic microorganisms. The aim of this study is to design multifunctional micelles for brain delivery of antimicrobial agents.
author2	Yang Yi Yan
author_facet	Yang Yi Yan Liu, Li Hong
format	Theses and Dissertations
author	Liu, Li Hong
author_sort	Liu, Li Hong
title	Antibiotic delivery across the blood-brain barrier by nanoparticle system
title_short	Antibiotic delivery across the blood-brain barrier by nanoparticle system
title_full	Antibiotic delivery across the blood-brain barrier by nanoparticle system
title_fullStr	Antibiotic delivery across the blood-brain barrier by nanoparticle system
title_full_unstemmed	Antibiotic delivery across the blood-brain barrier by nanoparticle system
title_sort	antibiotic delivery across the blood-brain barrier by nanoparticle system
publishDate	2009
url	https://hdl.handle.net/10356/20666
_version_	1759857768276164608

Antibiotic delivery across the blood-brain barrier by nanoparticle system

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