Brønsted acid catalyzed hydroamination and its application to total synthesis of cuspareine

An efficient method for the construction of 1,2-dihydroquinolines and its application to the total synthesis of cuspareine are reported herein. The method proceeds by protonation of the unactivated alkene, followed by an intramolecular cyclization with H2O as potentially the only by-product.

محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Bay, Siew Ting
مؤلفون آخرون: Philip Wai Hong Chan
التنسيق: Final Year Project
اللغة:English
منشور في: 2010
الموضوعات:
الوصول للمادة أونلاين:http://hdl.handle.net/10356/38932
الوسوم: إضافة وسم
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الوصف
الملخص:An efficient method for the construction of 1,2-dihydroquinolines and its application to the total synthesis of cuspareine are reported herein. The method proceeds by protonation of the unactivated alkene, followed by an intramolecular cyclization with H2O as potentially the only by-product.