Brønsted acid catalyzed hydroamination and its application to total synthesis of cuspareine

An efficient method for the construction of 1,2-dihydroquinolines and its application to the total synthesis of cuspareine are reported herein. The method proceeds by protonation of the unactivated alkene, followed by an intramolecular cyclization with H2O as potentially the only by-product.

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Bibliographic Details
Main Author:	Bay, Siew Ting
Other Authors:	Philip Wai Hong Chan
Format:	Final Year Project
Language:	English
Published:	2010
Subjects:	DRNTU::Science::Chemistry::Organic chemistry::Organic synthesis
Online Access:	http://hdl.handle.net/10356/38932
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Institution:	Nanyang Technological University
Language:	English

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spelling	sg-ntu-dr.10356-389322023-02-28T23:14:19Z Brønsted acid catalyzed hydroamination and its application to total synthesis of cuspareine Bay, Siew Ting Philip Wai Hong Chan School of Physical and Mathematical Sciences DRNTU::Science::Chemistry::Organic chemistry::Organic synthesis An efficient method for the construction of 1,2-dihydroquinolines and its application to the total synthesis of cuspareine are reported herein. The method proceeds by protonation of the unactivated alkene, followed by an intramolecular cyclization with H2O as potentially the only by-product. Bachelor of Science in Applied Physics 2010-05-21T01:39:56Z 2010-05-21T01:39:56Z 2010 2010 Final Year Project (FYP) http://hdl.handle.net/10356/38932 en 28 p. application/pdf
institution	Nanyang Technological University
building	NTU Library
continent	Asia
country	Singapore Singapore
content_provider	NTU Library
collection	DR-NTU
language	English
topic	DRNTU::Science::Chemistry::Organic chemistry::Organic synthesis
spellingShingle	DRNTU::Science::Chemistry::Organic chemistry::Organic synthesis Bay, Siew Ting Brønsted acid catalyzed hydroamination and its application to total synthesis of cuspareine
description	An efficient method for the construction of 1,2-dihydroquinolines and its application to the total synthesis of cuspareine are reported herein. The method proceeds by protonation of the unactivated alkene, followed by an intramolecular cyclization with H2O as potentially the only by-product.
author2	Philip Wai Hong Chan
author_facet	Philip Wai Hong Chan Bay, Siew Ting
format	Final Year Project
author	Bay, Siew Ting
author_sort	Bay, Siew Ting
title	Brønsted acid catalyzed hydroamination and its application to total synthesis of cuspareine
title_short	Brønsted acid catalyzed hydroamination and its application to total synthesis of cuspareine
title_full	Brønsted acid catalyzed hydroamination and its application to total synthesis of cuspareine
title_fullStr	Brønsted acid catalyzed hydroamination and its application to total synthesis of cuspareine
title_full_unstemmed	Brønsted acid catalyzed hydroamination and its application to total synthesis of cuspareine
title_sort	brønsted acid catalyzed hydroamination and its application to total synthesis of cuspareine
publishDate	2010
url	http://hdl.handle.net/10356/38932
_version_	1759855219077808128

Brønsted acid catalyzed hydroamination and its application to total synthesis of cuspareine

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