Towards the total synthesis of apicularen A

This thesis involves the synthesis of an intermediate towards Apicularen A utilizing indium-mediated conjugate addition of a thioester derived ketene to a conjugated ketone. This yields the important trans-2,6-hydroxypyran ring essential for its bioactivity as a potential anti-cancer agent.

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書目詳細資料
主要作者: Chan, Jocelyn Li Ting
其他作者: Loh Teck Peng
格式: Theses and Dissertations
語言:English
出版: 2010
主題:
在線閱讀:http://hdl.handle.net/10356/41762
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