Studies on the synthesis of tetrahydropyrans via oxa-Michael addition leading towards the total synthesis of Montanacin D
The first chapter describes a facile stereochemical study and synthetic route towards di-substituted tetrahydropyran rings. The key steps performed in this section involve cross-metathesis and Ozone-Wittig reactions of each alkene substrate, followed by an efficient oxa-Michael cyclisation to give t...
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| Format: | Thesis-Doctor of Philosophy |
| Language: | English |
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Nanyang Technological University
2021
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| Online Access: | https://hdl.handle.net/10356/148132 |
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| Institution: | Nanyang Technological University |
| Language: | English |