A synthesis of cyanolide A by intramolecular oxa-Michael addition

A synthesis of cyanolide A, a diolide natural product, has been achieved using a diastereoselective Barbier reaction, early-stage glycosylation, and intramolecular oxa-Michael addition to form the THP ring.

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Bibliographic Details
Main Authors: Bates, Roderick Wayland, Lek, Tee Guan
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2014
Subjects:
Online Access:https://hdl.handle.net/10356/103107
http://hdl.handle.net/10220/24360
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Institution: Nanyang Technological University
Language: English