A synthesis of cyanolide A by intramolecular oxa-Michael addition
A synthesis of cyanolide A, a diolide natural product, has been achieved using a diastereoselective Barbier reaction, early-stage glycosylation, and intramolecular oxa-Michael addition to form the THP ring.
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2014
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sg-ntu-dr.10356-1031072023-02-28T19:23:06Z A synthesis of cyanolide A by intramolecular oxa-Michael addition Bates, Roderick Wayland Lek, Tee Guan School of Physical and Mathematical Sciences Science::Chemistry::Organic chemistry::Organic synthesis Michael Addition Barbier Reaction A synthesis of cyanolide A, a diolide natural product, has been achieved using a diastereoselective Barbier reaction, early-stage glycosylation, and intramolecular oxa-Michael addition to form the THP ring. Accepted version 2014-12-09T02:11:47Z 2019-12-06T21:05:45Z 2014-12-09T02:11:47Z 2019-12-06T21:05:45Z 2014 2014 Journal Article Bates, R. W., & Lek, T. G. (2014). A synthesis of cyanolide A by intramolecular oxa-Michael addition. Synthesis, 46(13), 1731-1738. 0039-7881 https://hdl.handle.net/10356/103107 http://hdl.handle.net/10220/24360 10.1055/s-0033-1341153 en Synthesis Synthesis © 2014 Georg Thieme Verlag KG. This is the author created version of a work that has been peer reviewed and accepted for publication by Synthesis, Georg Thieme Verlag KG. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: [Article DOI: http://dx.doi.org/10.1055/s-0033-1341153]. 8 p. application/pdf |
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| topic |
Science::Chemistry::Organic chemistry::Organic synthesis Michael Addition Barbier Reaction |
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Science::Chemistry::Organic chemistry::Organic synthesis Michael Addition Barbier Reaction Bates, Roderick Wayland Lek, Tee Guan A synthesis of cyanolide A by intramolecular oxa-Michael addition |
| description |
A synthesis of cyanolide A, a diolide natural product, has been achieved using a diastereoselective Barbier reaction, early-stage glycosylation, and intramolecular oxa-Michael addition to form the THP ring. |
| author2 |
School of Physical and Mathematical Sciences |
| author_facet |
School of Physical and Mathematical Sciences Bates, Roderick Wayland Lek, Tee Guan |
| format |
Article |
| author |
Bates, Roderick Wayland Lek, Tee Guan |
| author_sort |
Bates, Roderick Wayland |
| title |
A synthesis of cyanolide A by intramolecular oxa-Michael addition |
| title_short |
A synthesis of cyanolide A by intramolecular oxa-Michael addition |
| title_full |
A synthesis of cyanolide A by intramolecular oxa-Michael addition |
| title_fullStr |
A synthesis of cyanolide A by intramolecular oxa-Michael addition |
| title_full_unstemmed |
A synthesis of cyanolide A by intramolecular oxa-Michael addition |
| title_sort |
synthesis of cyanolide a by intramolecular oxa-michael addition |
| publishDate |
2014 |
| url |
https://hdl.handle.net/10356/103107 http://hdl.handle.net/10220/24360 |
| _version_ |
1759856734125424640 |