Sequential michael addition/cyclisation : synthesis of multi-substituted naphthalenes.

• Main Author: Wang, Stephanie Qiu Mei.
• Other Authors: Zhong Guofu
• Format: Final Year Project
• Language: English
• Published: 2010
• Subjects: DRNTU::Science::Chemistry::Organic chemistry::Organic synthesis
• Online Access: http://hdl.handle.net/10356/39938
• Institution: Nanyang Technological University

Naphthalene derivatives have been found in many pharmaceuticals and luminescent materials. Herein, we report a tandem Michael Addition/Cyclisation utilizing aminocatalysis and Lewis acid catalysis to synthesize useful naphthalene derivatives under mild conditions. The Michael addition can work for a...