Cyclisation reactions for the synthesis of natural and unnatural piperidines

This work describes the platinum mediated ring opening isomerisation of 2,3-cyclopropanated piperidines, which results in either an endo or exocyclic olefin product. In the case where the beta-hydrogen is absent, a platinum-mediated Wagner-Meerwein type 1,2-alkyl shift reaction is observed. A sere...

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Bibliographic Details
Main Author: Barat, Viktor
Other Authors: Roderick Wayland Bates
Format: Theses and Dissertations
Language:English
Published: 2017
Subjects:
Online Access:http://hdl.handle.net/10356/72882
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Institution: Nanyang Technological University
Language: English