Effect of recombinant Wnt protein on the Ex vivo expansion of umbilical cord blood hematopoietic cells.

• Main Author: Lim, Shy Ni.
• Other Authors: School of Biological Sciences
• Format: Final Year Project
• Language: English
• Published: 2010
• Subjects: DRNTU::Science::Biological sciences::Genetics
• Online Access: http://hdl.handle.net/10356/39393
• Institution: Nanyang Technological University

Wnt gene pathway has shown to play an important role in the maintenance and development of hematopoietic stem cells (HSCs) compartment. The low number of HSCs in each umbilical cord blood (UCB) unit has limited its use in transplantation for adult patients. Therefore, a new method to expand these ce...