Generation of lentiviral-mediated shRNA vectors to inhibit the expression of caspase-1 and Pycard/ASC in dendritic cells.

Dendritic cells (DC) originate from hematopoietic precursors and they detect endogenous and exogenous stimuli which lead to an inflammatory response. The “inflammasome” is a large protein complex which consists of Caspase-1 and Pycard/ASC which are involved in IL-1β and IL-18 processing. However, th...

Full description

Saved in:
Bibliographic Details
Main Author: Tan, Bee Kim.
Other Authors: School of Biological Sciences
Format: Final Year Project
Language:English
Published: 2010
Subjects:
Online Access:http://hdl.handle.net/10356/39450
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Nanyang Technological University
Language: English
Be the first to leave a comment!
You must be logged in first