HAMLET mediates neural stem cell proliferation and differentiation.

• Main Author: Tay, Wei Ting.
• Other Authors: School of Biological Sciences
• Format: Final Year Project
• Language: English
• Published: 2010
• Subjects: DRNTU::Science::Biological sciences::Biochemistry
• Online Access: http://hdl.handle.net/10356/39491
• Institution: Nanyang Technological University

HAMLET (Human alpha-lactalbumin made lethal to tumor cells), a tumoricidal complex, was shown to trigger proliferation in immortalized human neural stem cells (hNSCs). In this study, I investigated the effects of HAMLET on the survivability, proliferation and neuronal differentiation of primary mou...