Receptor mediated adhesion under external stimuli
Many studies have shown that Epigallocatechin-3-gallate (EGCG) from green tea, exhibits therapeutic effects that inhibits cancer invasion and metastasis and affects cell proliferation and death Since cell adhesion is an important process that regulates cell migration, the effects of EGCG on cell...
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| Format: | Final Year Project |
| Language: | English |
| Published: |
2010
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| Subjects: | |
| Online Access: | http://hdl.handle.net/10356/39563 |
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| Institution: | Nanyang Technological University |
| Language: | English |
| Summary: | Many studies have shown that Epigallocatechin-3-gallate (EGCG) from green tea,
exhibits therapeutic effects that inhibits cancer invasion and metastasis and affects cell
proliferation and death Since cell adhesion is an important process that regulates cell
migration, the effects of EGCG on cell adhesion is investigated to understand more on its
therapeutic effects. This study demonstrated that HepG2 cell cultured with increasing
concentration of EGCG results in an increase in rate of adhesion contact area, degree of
cell deformation and average adhesion energy of cell. The inhibition of cell migration by
EGCG was also observed, which supports the evidence of therapeutic effects from
EGCG. |
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